Joint seminars and meetings
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| Kick-off Meeting |
2009 |
Date: 17-21 October 2009
Venue: Vienna, Austria
 
Coordinators
Prof. Yoshiki Sawa
Dept. of Cardiovascular Surgery
Osaka University Graduate School of Medicine Osaka, Japan
Prof. Ari Harjula
Dept. of Cardiothoracic Surgery
University of Helsinki Helsinki, Finland
Prof. Axel Haverich
Dept. Cardiothoracic, Transplantation, and Vascular Surgery
Hannover Medical School Hannover, Germany
 Photo Gallery
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| Professor Harjula (Helsinki University) invited to Japan |
2010 |
Date：10-12 March 2010
Venue：Kyoto University
Osaka University
 
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| Leaders Meeting |
Date：3 May 2010
Venue: Intercontinental Hotel Toronto Centre
 
Photo Gallery
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| Progress Meeting |
Date：12 September 2010
Venue: Saas Fee Room (First floor), Crowne Plaza Hotel Geneva
 
       
Photo Gallery
Video Gallery
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Results and schedule of young researcher exchange |
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Publication achievements for International Collaboration
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| Publication achievements |
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Kitabayashi K, Siltanen A, P .A Ndtil Nd T, Mahar MA, Tikkanen I, Koponen J, Ono M, Sawa Y, Kankuri E, Harjula A.
Bcl-2 expression enhances myoblast sheet transplantation therapy for acute myocardial infarction.
CELL TRANSPLANTATION. 2010;19(5):573-88.
Helsinki
A Siltanen, K Kitabayashi, Esko Kankuri, Ari Harjula, et, al.
Bcl-2 enhances the therapeutic paracrine effect of myoblast sheets in rat chronic heart failure.
2008 ESAO, 2009 J.Cell Tx
A Siltanen, K Kitabayashi, Esko Kankuri, Ari Harjula, et, al.
Inhibition of apoptosis by Bcl-2 expression enhances myoblast sheet transplantation for acute myocardial infarction.
2010 J. Cell Tx
Hannover
H Hata, A baer, Y Sawa, A Haverich, A Hilfiker, et, al.
In vitro engineering of 3-dimensional myocardial patch with cardiomyocyte sheets and decellularized matrix.
2009 EACTS, EJCTS
H Ide, M Ono, Y Sawa, A Haverich, T Breymann et, al.
Clinical outcome of patients 30 years after surgical repair of tetralogy of Fallot.
2009 EACTS
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Promotion of clinical application of cell sheet transplantation on Osaka University
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| Development of cell sheet transplantation on Osaka University |
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| Ongoing clinical trials of cell sheets |
| 1．Development of novel therapy using autologous cell sheet transplantation in patients with severe heart failure.
Patirnts: DCM 5 cases, ICM 5 cases (without LVAD)
Until now 1 case for DCM and 4 cases for ICM performed
2．Myoblast cell sheet transplantation for the patients with DCM with LDAS; safety and feasibility study.
4 cases performed
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| Development of new cell sheet |
Introduction of iPS cells ( collaboration with Kyoto University )
By transplantation of beating myocardial cells, transplanted cells will synchronize
with host myocardium and cardiac contraction will be improved.
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| Clinical trials in International multiinstitutional of cell sheet transplantation |
Grant applications to the EU-Funding FP7 Program
International Multi-Center Clinical Trial Investigating Myoblast Cell Sheet Transplantation in
Patients with Severe Heart Failure.
5 years (2011~2016)
6-12 Million Euro.
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Construction achievements of International multilateral collaboration
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